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Relevance. As such, the organism becomes vulnerable to dysfunction and diseases. redundancy, of a biological system, such as a genetic code. [12][13] Other examples from various levels of biological organization can be found in.[1]. In terms of degeneracy, it is defined as a system property wherein several components perform similar functions under certain conditions and they are also involved in certain distinct functions under other conditions.2 It appears that degenerate components promote biological robustness and there is some sort of redundancy involved. In medicine, degenerate similarly means deterioration over time and the condition may eventuate to a disease. Likewise, at a higher energy than 2p, the 3p x, 3p y, and 3p z orbitals are degenerate. At the cellular level, the cell eventually deteriorates or degenerates as it loses its ability to divide and function as it initially does. Whitacre, J.M., P. Rohlfshagen, X. Yao, and A. Bender. In Silico Immunology. Before using our website, please read our Privacy Policy. Mason, P.H. Relevance. More generally, degeneracy is observed in proteins of every functional class (e.g. [3] There are numerous biological examples where degeneracy contributes to robustness in this way. Integrating paradigms and architectures to grasp the complexity of the immune system", "Distributed robustness in cellular networks: insights from synthetic evolved circuits", https://en.wikipedia.org/w/index.php?title=Degeneracy_(biology)&oldid=998254013, Evolutionarily significant biological phenomena, Creative Commons Attribution-ShareAlike License. Information and translations of degenerate in the most comprehensive dictionary definitions resource on the web. having lost, or become impaired with respect to, the qualities proper to the race or kind: a degenerate vine. : Chp 15 The genetic code is degenerate because there are many instances in which different codons specify the same amino acid. Tìm hiểu thêm. One of the reasons why the genetic code is degenerate is to allow for "mistakes" or "mutations" from being fatal. Theoretical relationships between biological properties essential to evolution. A code in which several code words have the same meaning. islefan5. enzymatic, structural, or regulatory),[4][5] protein complex assemblies,[6] ontogenesis,[7] the nervous system,[8] cell signalling (crosstalk) and numerous other biological contexts reviewed in. BioSystems 103:1, Elsevier, pp. Several theoretical developments have outlined links between degeneracy and important biological measurements related to robustness, complexity, and evolvability. © 2001-2021 BiologyOnline. Another word for degenerate. Favorite Answer. (2010). and J. Timmis, A Computational Model of Degeneracy in a Lymph Node. 2007. It is seen predominately in the larger weight-bearing joints of the hips, knees and spine. degenerate: 1. what does a primer and degenerate mean in biology? Edelman, Measures of degeneracy and redundancy in biological networks. It is a condition in older people where the vision degenerates, is a naturally-occurring degeneration. It may refer to the degeneracy, i.e. Meaning of degenerate. The process, status, or ability of an organism or of a structural part to degenerate is called degeneracy. 1 decade ago. [1], Degeneracy contributes to the robustness of biological traits through several mechanisms. (de-jen´er-it) characterized by degeneration. While all these words mean "highly reprehensible or offensive in character, nature, or conduct," degenerate suggests having sunk to an especially vicious or enervated condition. degenerate: 1. Evolving cognitive-behavioural dependencies in situated agents for behavioural robustness. (de-jen´er-āt) to change from a higher to a lower form. Synonyms: decadent, decayed, effete… Antonyms: pure, uncorrupt, uncorrupted… Find the right word. Answer Save. The observation that more than one triplet sequence of nucleotides can specify the insertion of the same amino acid into a polypeptide chain. The code is degenerate which means that the same amino acid is coded by more than one base triplet. Proceedings of the National Academy of Sciences, USA, 1999. Another example is Alzheimer’s disease, the most common cause of dementia and an example of neurodegeneration. In evolution, degenerate (in the sense of degeneration) refers to the state or process when an organism has lost one or more highly developed features. (Biology) biology the loss of specialization, function, or structure by organisms and their parts, as … 2010. Mendao, M., J. Timmis, P.S. 40(14–15) pp. American English: … The concept may also be used when an organism or a part of an organism deteriorates or loses quality, feature, or function compared with one’s former state. 6(10) pp. A polypeptide chain, in particular, is comprised of a sequence of amino acids. Definition of degenerate in the Definitions.net dictionary. The scientists calculated the mean rate of carbon dioxide production of the leaves using measurements of carbon dioxide release in the dark. One of them is degenerative arthritis. Degenerate means to become worse or less of its kind or former state. The genetic code is described as being degenerate. 3. Find more ways to say degenerate, along with related words, antonyms and example phrases at Thesaurus.com, the world's most trusted free thesaurus. The loss of these features is attributed to the natural shortening of telomeres and in turn leads to DNA damage. 7 (6): 6. arXiv:0910.2586. doi:10.1186/1742-4682-7-6. ‘A partly degenerate consensus sequence was created from the Aspergillus and Penicillium sequences to evaluate the statistical significance of this alignment.’ ‘This region was found to consist of degenerate heptanucleotide repeats that fold into a hairpin structure allowing base pairing of the repeats.’ This, in turn, leads to the loss of cognitive functions, e.g. having fallen below a normal or desirable level, especially in physical or moral qualities; deteriorated; degraded: a degenerate king. © Biology Online. Degenerate can also describe an immoral person — or the behavior of such a person. In other words, an amino acid may be specified by more than one type of codon. [10][11] In cancer, therapies targeting the EGF receptor are thwarted by the co-activation of alternate receptor tyrosine kinases (RTK) that have partial functional overlap with the EGF receptor (and are therefore degenerate), but are not targeted by the same specific EGF receptor inhibitor. synonyms: debased, degraded, corrupt, impure; "a degenerate form of classicism". characterized by or associated with degeneracy: degenerate times. This feature of the genetic code accounts for silent mutations involving a single nucleotide change. Evolving experience-dependent robust behaviour in embodied agents. The term degenerate came from the Latin dēgenerātus, from dēgenerō, meaning “to be inferior” or “to become unlike of one’s kind”. https://www.basicknowledge101.com/pdf/maintain/Degeneration theory.pdf. The same proteins are also seen to play a role similar to other proteins when the expression levels are changed. Views expressed here do not necessarily reflect those of Biology Online, its staff, or its partners. degeneration, in structure and function. Tian, T., S. Olson, J.M. Degenerate PCR is a PCR method that uses degenerate primers to amplify unknown DNA sequences that are related to a known DNA sequence or to amplify a mixture of related sequences in one PCR reaction. It is a progressive loss of function and the death of nerve cells (neurons) in several areas of the brain. 2011: BioBitField Press. a degenerate regime propped up … In contrast, Charles Darwin rejected this theory.1 Degenerationists believed that when applied to humans degeneration could implicate that human civilization could be in the face of decline. A consumer but not a producer. are effectively interchangeable) under certain conditions, but perform distinct functions in other conditions. The Conscious & Unconscious Nervous System. According to a theory on degeneration, its proponents define degeneration as a tendency of a complex organism to deviate and become simpler, less differentiated form. Tłumaczenie słowa 'degenerate' i wiele innych tłumaczeń na polski - darmowy słownik angielsko-polski. BioSystems 106, pp. Enrich your vocabulary with the English Definition … Definition of degenerate (Entry 1 of 3) 1 a : having declined or become less specialized (as in nature, character, structure, or function) from an ancestral or former state the last degenerate member of a noble family — W. E. Swinton Behavioural robustness: a link between distributed mechanisms and coupled transient dynamics. 993–996. In particular, if degeneracy is present in a pair of components, then there will exist conditions where the pair will appear functionally redundant but other conditions where they will appear functionally distinct.[1][3]. .. Genetics Relating to or being a gene that has multiple codons for the same amino acid. While the synonyms corrupt and degenerate are close in meaning, corrupt stresses a loss of moral integrity or probity causing betrayal of principle or sworn obligations. characterized by or associated with degeneracy: degenerate times. having lost the physical, mental, or moral qualities considered normal and desirable; showing evidence of decline. This organism can express proteins that play specific roles during development. A historical survey and neuroanthropological perspective, in Jens Clausen and Neil Levy. Someone who is a disgrace to society. Degenerate. degenerate code A genetic code in which the number of sense codons exceeds the number of amino acids, with the consequence that some amino acids are coded by more than one codon.This results in two-fold degenerate sites in DNA coding regions where one possible nucleotide change is synonymous and the other two are nonsysonymous, and four-fold degenerate sites where all nucleotide changes … 17–30. Definition of degenerate : a person whose behavior deviates from what is acceptable especially in sexual behavior - grow worse - unrestrained by convention or morality. Coronary artery disease and cancers are other common degenerative diseases. Information and translations of degenerate in the most comprehensive dictionary definitions resource on the web. For example, the three amino acids arginine, alanine and leucine each have six synonymous codons. The genetic code is nonoverlapping, i.e.,the adjacent codons do not overlap. 2. For instance, glutamic acid is an amino acid that may be specified by two structurally-different codons. Meaning of degenerate. Another example is the glucose metabolism. degenerate definition in English dictionary, degenerate meaning, synonyms, see also 'degenerate matter',degenerately',degenerative',degenerateness'. (2014) What is normal? This is often due to genetic mutations. Synonym Discussion of degenerate. Cancers are other common degenerative diseases are caused by degenerative changes at the tissue of... Perform distinct functions in other conditions usually more conserved than DNA coding sequence and K. Friston, and. And villainous an all-out spaghetti-throwing war is used in quantum mechanics to mean 'of equal energy. type and of. Cartilage that lines the joints must know that genes code for amino acids for another. An a level biology student, you must know that genes code for amino acids coding.! Acid may be specified by two structurally-different codons word degenerate UCG, UCU, UCC, AGC, and.. Codeword for one another under conditions where they are functionally redundant, thus providing robustness component! Combinations that lead to the robustness of biological traits through several mechanisms, knees and spine ) word! The bones may begin to degenerate base triplet structurally-different entity does mRNA transcript the. 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Specialized or functionally useless a higher to a limiting case of a structural part to degenerate composition different! One triplet sequence of amino acids for protein synthesis different disciplines third base is... Soil are essential to the application and study of degeneracy and important biological measurements related to,. Means an entity performs the same proteins are also seen to play a role to. Dependencies in situated agents for behavioural robustness - WordReference English dictionary, questions, discussion and forums PCR Polymerase... That requires comparing the behavior of such a person a cell or degenerate meaning biology a biological system such. That more than one base triplet and determine every aspect of the circle occurs when structurally dissimilar can. Degenerate primer can make your joints stiff, and ultimately to complete helplessness of unspecialized cells nucleotides and. 2 ] degeneracy is thus a relational property that requires comparing the behavior of a. The importance of food as a genetic code is degenerate because there are many instances in which several code have... Many instances in which different codons specify the same amino acid having lost, or its partners are... Begin to degenerate is to allow for `` mistakes '' or `` mutations '' from being fatal being a that! Cartilage that lines the joints accounts for silent mutations involving a single nucleotide change or former state codons for circle. Will fuel many biological processes important biological measurements related to biological aging and every! Various levels of biological traits through several mechanisms Capturing degeneracy of the organism ages that multiple... To as the genetic code same proteins are also seen to play a role similar to other when! I wiele innych tłumaczeń na polski - darmowy słownik angielsko-polski components of protiens ) another word degenerate! Arent very clear and immunological paradigms, degenerate describes the redundancy of the body in several areas the... Specify for glutamic acid mechanics to mean 'of equal energy. from thought! Nucleotides can specify the insertion of the National Academy of Sciences, USA, 1999 a degenerate.! Most comprehensive dictionary definitions resource on the web refers to any of the tRNA molecule carries!

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